Intermédiaire pharmaceutique

3-fluoro-1-propan-2-yloxycarbonylcyclobutane-1-carboxylic acid structure
SL1112001
3-fluoro-1-propan-2-yloxycarbonylcyclobutane-1-carboxylic acid
CAS 1403766-90-4
Esqueleto de ciclobutano Ácido carboxílico Bloque de anillo pequeño Intermediario farmacéutico
3-aminooxetane-3-carbonitrile;hydrochloride structure
SL1112002
3-aminooxetane-3-carbonitrile;hydrochloride
CAS 1818847-73-2
Esqueleto de oxetano Amina primaria Bloque heterocíclico Intermediario farmacéutico
tert-butyl 3-amino-3-(trifluoromethyl)azetidine-1-carboxylate structure
SL1112003
tert-butyl 3-amino-3-(trifluoromethyl)azetidine-1-carboxylate
CAS 1258652-24-2
Esqueleto de azetidina Amina primaria Bloque heterocíclico fluorado Intermediario farmacéutico
Spiro[2.3]hexan-5-one structure
SL1112004
Spiro[2.3]hexan-5-one
CAS 20061-22-7
Esqueleto espirocíclico Cetona Bloque de anillo pequeño Intermediario farmacéutico
Methyl 5,8-dioxaspiro[3.4]octane-2-carboxylate structure
SL1112005
Methyl 5,8-dioxaspiro[3.4]octane-2-carboxylate
CAS 1037175-81-7
Esqueleto de dioxaspiro Acetal Bloque espirocíclico Intermediario farmacéutico
tert-butyl N-[3,3-difluoro-1-(hydroxymethyl)cyclobutyl]carbamate structure
SL1112006
tert-butyl N-[3,3-difluoro-1-(hydroxymethyl)cyclobutyl]carbamate
CAS 1232365-42-2
Esqueleto de ciclobutano Amina protegida con Boc Bloque de anillo pequeño fluorado Intermediario farmacéutico
tert-butyl N-[3-fluoro-1-(hydroxymethyl)cyclobutyl]carbamate structure
SL1112007
tert-butyl N-[3-fluoro-1-(hydroxymethyl)cyclobutyl]carbamate
CAS 1232365-48-8
Esqueleto de ciclobutano Amina protegida con Boc Bloque de anillo pequeño fluorado Intermediario farmacéutico
5,8-dioxaspiro[3.4]octan-2-ylmethanol structure
SL1112008
5,8-dioxaspiro[3.4]octan-2-ylmethanol
CAS 545882-60-8
Esqueleto de dioxaspiro Acetal Bloque espirocíclico Intermediario farmacéutico
methyl azetidine-2-carboxylate;hydrochloride structure
SL1112009
methyl azetidine-2-carboxylate;hydrochloride
CAS 162698-26-2
Esqueleto de azetidina Amina secundaria Bloque heterocíclico Intermediario farmacéutico
(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-amine structure
SL1112010
(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-amine
CAS 87571-88-8
Amina puente Amina primaria Bloque de amina quiral Intermediario farmacéutico
spiro[3.3]heptan-2-one structure
SL1112011
spiro[3.3]heptan-2-one
CAS 30152-57-9
Esqueleto de espiro[3.3]heptano Cetona Bloque espirocíclico Intermediario farmacéutico
2-oxaspiro[3.3]heptan-6-one structure
SL1112012
2-oxaspiro[3.3]heptan-6-one
CAS 1339892-66-8
Esqueleto de oxaspiro Cetona Bloque espirocíclico Intermediario farmacéutico
tert-Butyl 2-(((tert-butyldiphenylsilyl)oxy)methyl)-3-formylazetidine-1-carboxylate structure
SL1112013
tert-Butyl 2-(((tert-butyldiphenylsilyl)oxy)methyl)-3-formylazetidine-1-carboxylate
CAS 1638771-11-5
Esqueleto de azetidina Alcohol protegido con sililo Intermediario heterocíclico protegido Intermediario farmacéutico
tert-butyl N-[(3-hydroxycyclobutyl)methyl]carbamate structure
SL1112014
tert-butyl N-[(3-hydroxycyclobutyl)methyl]carbamate
CAS 917827-92-0
Esqueleto de ciclobutano Alcohol Bloque de anillo pequeño Intermediario farmacéutico
tert-Butyl5,5-difluoro-2,7-diazaspiro[3.5]nonane-2-carboxylate structure
SL1112015
tert-Butyl5,5-difluoro-2,7-diazaspiro[3.5]nonane-2-carboxylate
CAS 2007920-32-1
Esqueleto de diazaspiro Amina protegida con Boc Bloque heterocíclico fluorado Intermediario farmacéutico
1-Amino-3-fluorocyclobutanecarboxylic acid structure
SL1112016
1-Amino-3-fluorocyclobutanecarboxylic acid
Esqueleto de ciclobutano Ácido carboxílico Bloque de anillo pequeño Intermediario farmacéutico
(cis-3-Aminocyclobutyl)methanol hydrochloride structure
SL1112017
(cis-3-Aminocyclobutyl)methanol hydrochloride
CAS 142733-65-1
Esqueleto de ciclobutano Alcohol Bloque de amina de anillo pequeño Intermediario farmacéutico
3,3-Dimethylcyclobutanecarboxylic acid structure
SL1112018
3,3-Dimethylcyclobutanecarboxylic acid
CAS 34970-18-8
Esqueleto de ciclobutano Ácido carboxílico Bloque de anillo pequeño Intermediario farmacéutico
tert-Butyl (cis-3-(hydroxymethyl)cyclobutyl)carbamate structure
SL1112019
tert-Butyl (cis-3-(hydroxymethyl)cyclobutyl)carbamate
CAS 142733-64-0
Esqueleto de ciclobutano Amina protegida con Boc Amina de anillo pequeño protegida Intermediario farmacéutico
3-Bromotetrahydrofuran structure
SL1112020
3-Bromotetrahydrofuran
CAS 19311-37-6
Esqueleto de tetrahidrofurano Bromuro de alquilo Bloque heterocíclico halogenado Intermediario farmacéutico
tert-butyl 3-(aminomethyl)-1-oxa-9-azaspiro[4.5]decane-9-carboxylate structure
SL1112021
tert-butyl 3-(aminomethyl)-1-oxa-9-azaspiro[4.5]decane-9-carboxylate
CAS 1160247-18-6
Esqueleto de oxa-azaspiro Amina protegida con Boc Bloque heterocíclico espiro Intermediario farmacéutico
3-(Difluoromethyl)azetidine hydrochloride structure
SL1112022
3-(Difluoromethyl)azetidine hydrochloride
CAS 1354792-76-9
Esqueleto de azetidina Grupo difluorometilo Bloque heterocíclico fluorado Intermediario farmacéutico
(2S,4S)-4-phenylsulfanylpyrrolidine-2-carboxylic acid;hydrochloride structure
SL1112023
(2S,4S)-4-phenylsulfanylpyrrolidine-2-carboxylic acid;hydrochloride
CAS 105107-84-4
Esqueleto de prolina Ácido carboxílico Bloque de aminoácido quiral Intermediario farmacéutico
3-Methyl-3-azetidinecarboxylic acid methyl ester hydrochloride structure
SL1112024
3-Methyl-3-azetidinecarboxylic acid methyl ester hydrochloride
CAS 1114876-08-2
Esqueleto de azetidina Éster metílico Bloque de éster heterocíclico Intermediario farmacéutico
(1-Methylazetidin-3-yl)methanamine structure
SL1112025
(1-Methylazetidin-3-yl)methanamine
CAS 1359656-98-6
Esqueleto de azetidina Amina primaria Bloque de amina heterocíclica Intermediario farmacéutico
3-Fluoro-3-methylazetidine hydrochloride structure
SL1112026
3-Fluoro-3-methylazetidine hydrochloride
CAS 1427379-42-7
Esqueleto de azetidina Heterociclo fluorado Bloque heterocíclico fluorado Intermediario farmacéutico
2-(Oxetan-3-yl)ethan-1-ol structure
SL1112027
2-(Oxetan-3-yl)ethan-1-ol
CAS 251922-46-0
Esqueleto de oxetano Alcohol Bloque de anillo pequeño oxigenado Intermediario farmacéutico
1-Tert-butyl 3-methyl 3-hydroxyazetidine-1,3-dicarboxylate structure
SL1112028
1-Tert-butyl 3-methyl 3-hydroxyazetidine-1,3-dicarboxylate
CAS 1884303-05-2
Esqueleto de azetidina Alcohol terciario Intermediario heterocíclico protegido Intermediario farmacéutico
[(3-Methylidenecyclobutoxy)methyl]benzene structure
SL1112029
[(3-Methylidenecyclobutoxy)methyl]benzene
CAS 1057641-73-2
Esqueleto de metilenciclobutano Alqueno Bloque de alqueno de anillo pequeño Intermediario farmacéutico
Tert-butyl 3-amino-3-ethylazetidine-1-carboxylate structure
SL1112030
Tert-butyl 3-amino-3-ethylazetidine-1-carboxylate
CAS 1158758-79-2
Esqueleto de azetidina Amina primaria Bloque de amina heterocíclica Intermediario farmacéutico
2-Methylene-5,8-dioxaspiro[3.4]octane structure
SL1112031
2-Methylene-5,8-dioxaspiro[3.4]octane
CAS 99620-40-3
Esqueleto de dioxaspiro Acetal Bloque espirocíclico Intermediario farmacéutico
(4,4-Dimethyloxetan-2-yl)methanol structure
SL1112032
(4,4-Dimethyloxetan-2-yl)methanol
CAS 61266-55-5
Esqueleto de oxetano Alcohol Bloque de anillo pequeño oxigenado Intermediario farmacéutico
2-Oxaspiro[3.3]heptan-6-ylmethanol structure
SL1112033
2-Oxaspiro[3.3]heptan-6-ylmethanol
CAS 1363380-95-3
Esqueleto de oxaspiro Alcohol Bloque espirocíclico Intermediario farmacéutico
1-Amino-3,3-difluorocyclobutanecarboxylic acid structure
SL1112034
1-Amino-3,3-difluorocyclobutanecarboxylic acid
CAS 1225532-86-4
Esqueleto de ciclobutano Ácido carboxílico Bloque de anillo pequeño fluorado Intermediario farmacéutico
3-(Bromomethyl)-1,1-dimethylcyclobutane structure
SL1112035
3-(Bromomethyl)-1,1-dimethylcyclobutane
CAS 76207-22-2
Esqueleto de ciclobutano Bromuro de alquilo Bloque alquilante de anillo pequeño Intermediario farmacéutico
1-benzylpiperidine-4-carbaldehyde structure
SL1112036
1-benzylpiperidine-4-carbaldehyde
CAS 22065-85-6
Esqueleto de piperidina Aldehído Bloque de aldehído heterocíclico Intermediario farmacéutico
4-Chloro-5H-pyrrolo[3,2-d]pyrimidin-2-amine structure
SL1112038
4-Chloro-5H-pyrrolo[3,2-d]pyrimidin-2-amine
CAS 943736-58-1
Esqueleto de pirrolopirimidina Cloruro de heteroarilo Bloque de inhibidor de cinasa Intermediario farmacéutico
N-benzyl-2-chloroethanamine;hydrochloride structure
SL1112039
N-benzyl-2-chloroethanamine;hydrochloride
CAS 6288-63-7
Esqueleto de bencilamina Amina secundaria Bloque de amina alquilante Intermediario farmacéutico
N-(2,4-ditert-butyl-5-hydroxyphenyl)acetamide structure
SL1112043
N-(2,4-ditert-butyl-5-hydroxyphenyl)acetamide
CAS 1992813-92-9
Motivo fenol impedido Acetanilida Bloque aromático funcional Intermediario farmacéutico
3-(4-chlorophenyl)-3-methoxyazetidine;hydrochloride structure
SL1113001
3-(4-chlorophenyl)-3-methoxyazetidine;hydrochloride
CAS 1781544-25-9
Esqueleto de azetidina Grupo metoxi Bloque de arilazetidina Intermediario farmacéutico
(2R,4R)-4-Methylpiperidine-2-carboxylic acid structure
SL1113002
(2R,4R)-4-Methylpiperidine-2-carboxylic acid
CAS 74892-81-2
Esqueleto de piperidina Ácido carboxílico Bloque de aminoácido quiral Intermediario farmacéutico
Ethyl (2R,4R)-4-methyl-2-piperidinecarboxylate structure
SL1113003
Ethyl (2R,4R)-4-methyl-2-piperidinecarboxylate
CAS 74892-82-3
Esqueleto de piperidina Éster etílico Bloque de éster de aminoácido quiral Intermediario farmacéutico
tert-Butyl aziridine-1-carboxylate structure
SL1113004
tert-Butyl aziridine-1-carboxylate
CAS 97308-23-1
Esqueleto de aziridina Amina protegida con Boc Bloque de aza-anillo pequeño Intermediario farmacéutico
1,1-Cyclopropanedicarboxylic acid structure
SL1113005
1,1-Cyclopropanedicarboxylic acid
CAS 598-10-7
Esqueleto de ciclopropano Ácido dicarboxílico Bloque de diácido de anillo pequeño Intermediario farmacéutico
2-oxooxolane-3-carboxylic acid structure
SL1113006
2-oxooxolane-3-carboxylic acid
CAS 4360-91-2
Esqueleto de oxolanona Ácido carboxílico Bloque de heterociclo de oxígeno Intermediario farmacéutico
(1R,2S)-2-Fluorocyclopropylaminetosylate structure
SL1113007
(1R,2S)-2-Fluorocyclopropylaminetosylate
CAS 143062-84-4
Esqueleto de ciclopropano Amina primaria Bloque de amina fluorada quiral Intermediario farmacéutico
3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one structure
SL1113008
3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one
CAS 3680-71-5
Esqueleto de pirrolopirimidina Lactama Bloque de heteroarilo farmacéutico Intermediario farmacéutico
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine structure
SL1113009
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine
CAS 3680-69-1
Esqueleto de pirrolopirimidina Cloruro de heteroarilo Bloque de inhibidor de cinasa Intermediario farmacéutico
2,4-Dichloro-7H-pyrrolo[2,3-d]pyriMidine structure
SL1113010
2,4-Dichloro-7H-pyrrolo[2,3-d]pyriMidine
CAS 90213-66-4
Esqueleto de pirrolopirimidina Heteroareno dicloro Precursor de funcionalización de heteroarilo Intermediario farmacéutico
3-Methyl-8-quinolinesulphonyl chloride structure
SL1113011
3-Methyl-8-quinolinesulphonyl chloride
CAS 74863-82-4
Esqueleto de quinolina Cloruro de sulfonilo Reactivo de sulfonilación Intermediario farmacéutico
3-Bromo-5-chloro-4-hydroxyaniline structure
SL1113013
3-Bromo-5-chloro-4-hydroxyaniline
CAS 1158322-54-3
Aminofenol halogenado Amina aromática Bloque de arilamina halogenada Intermediario farmacéutico
2-(4-Bromomethyl)phenylpropionic acid structure
SL1113014
2-(4-Bromomethyl)phenylpropionic acid
CAS 111128-12-2
Esqueleto de ácido arilpropiónico Ácido carboxílico Bloque aromático alquilante Intermediario farmacéutico
1-bromo-2-(2-methoxyethoxy)ethane structure
SL1113015
1-bromo-2-(2-methoxyethoxy)ethane
CAS 54149-17-6
Motivo de cadena éter Bromuro de alquilo Bloque enlazador Intermediario farmacéutico
(S)-(+)-1-Bromo-2-methylbutane structure
SL1113020
(S)-(+)-1-Bromo-2-methylbutane
CAS 534-00-9
Cadena alquilo quiral Bromuro de alquilo Bloque quiral alquilante Intermediario farmacéutico
4-(2-amino-2-methylpropyl)phenol structure
SL1113021
4-(2-amino-2-methylpropyl)phenol
CAS 51706-55-9
Motivo aminofenol Amina primaria Bloque de arilamina Intermediario farmacéutico
1,3-dimethyl-5-(methylamino)-4-pyrazolyl o-fluorophenyl ketone structure
SL1113022
1,3-dimethyl-5-(methylamino)-4-pyrazolyl o-fluorophenyl ketone
CAS 56877-15-7
Esqueleto de pirazol Cetona de arilo Bloque de heteroarilo fluorado Intermediario farmacéutico
4-ethynyl-1,2-bis(trifluoromethyl)benzene structure
SL1113023
4-ethynyl-1,2-bis(trifluoromethyl)benzene
CAS 2411969-93-0
Bis(trifluorometil)benceno Alquino terminal Bloque de areno etinilo Intermediario farmacéutico
3,5-diisopropylphenol structure
SL1113024
3,5-diisopropylphenol
CAS 26886-05-5
Motivo diisopropilfenol Fenol Bloque de fenol impedido Intermediario farmacéutico
3-Hydroxy-4- nitrobenzoic Acid structure
SL1113028
3-Hydroxy-4- nitrobenzoic Acid
CAS 619-14-7
Esqueleto de ácido nitrobenzoico Ácido carboxílico Bloque de ácido nitroarílico Intermediario farmacéutico
4-ethynyl-1,2-bis(trifluoromethyl)benzene structure
SL1213019
4-ethynyl-1,2-bis(trifluoromethyl)benzene
CAS 2411969-93-0
Bis(trifluorometil)benceno Alquino terminal Bloque de areno etinilo Intermediario farmacéutico
Acetoacetamide structure
SL1310002
Acetoacetamide
CAS 5977-14-0
amida compuesto carbonílico enolizable bloque de construcción sintético bloque de construcción general