tert-butyl N-[3-fluoro-1-(hydroxymethyl)cyclobutyl]carbamate

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tert-butyl N-[3-fluoro-1-(hydroxymethyl)cyclobutyl]carbamate structure
Structural Feature
Cyclobutane scaffold
Reactive Feature
Boc-protected amine Fluorocyclobutane Hydroxymethyl group
Synthesis Role
Fluorinated small-ring building block
Application Context
Pharmaceutical intermediate
Número CAS1232365-48-8
N.º CE/lista895-601-5
Fórmula molecularC10H18FNO3
Masa molar219.25 g/mol
AspectoWhite solid
SMILESCC(C)(C)OC(=O)NC1(CO)CC(F)C1
InChIKeyMLIXJRTXFCDVNT-UHFFFAOYSA-N
Descripcióntert-Butyl N-[3-fluoro-1-(hydroxymethyl)cyclobutyl]carbamate, a monofluorinated cyclobutane aminomethyl building block. Fluorine tunes conformational preference and metabolic stability.
AplicacionesPharmaceutical intermediate; fluorinated building block; cyclobutane; Boc-protected