4-Chloro-5H-pyrrolo[3,2-d]pyrimidin-2-amine

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4-Chloro-5H-pyrrolo[3,2-d]pyrimidin-2-amine structure
Structural Feature
Pyrrolopyrimidine scaffold
Reactive Feature
Amino heteroarene Heteroaryl chloride
Synthesis Role
Kinase inhibitor building block
Application Context
Pharmaceutical intermediate
CAS Number943736-58-1
Product CodeSL1112038
Molecular FormulaC6H5ClN4
Molecular Weight168.58
Boiling Point472.3±48.0 °C (Predicted)
Density1.643±0.06 g/cm³ (Predicted)
SMILESNc1nc(Cl)c2[nH]ccc2n1
InChIKeyNCSPBRYDQWLYLE-UHFFFAOYSA-N
Description4-Chloro-5H-pyrrolo[3,2-d]pyrimidin-2-amine, a chloroamino pyrrolopyrimidine. The 4-chloro is a nucleophilic aromatic substitution handle for kinase inhibitor synthesis.
ApplicationsPharmaceutical intermediate; pyrrolopyrimidine; kinase inhibitor intermediate

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