tert-butyl N-[3,3-difluoro-1-(hydroxymethyl)cyclobutyl]carbamate

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tert-butyl N-[3,3-difluoro-1-(hydroxymethyl)cyclobutyl]carbamate structure
Structural Feature
Cyclobutane scaffold
Reactive Feature
Boc-protected amine Difluoro substituted Hydroxymethyl group
Synthesis Role
Fluorinated small-ring building block
Application Context
Pharmaceutical intermediate
CAS Number1232365-42-2
Product CodeSL1112006
EC Number846-336-9
Molecular FormulaC10H17F2NO3
Molecular Weight237.24
AppearanceYellow solid
SMILESCC(C)(C)OC(=O)NC1(CO)CC(F)(F)C1
InChIKeyRNZVBWMKWVRXIY-UHFFFAOYSA-N
Descriptiontert-Butyl N-[3,3-difluoro-1-(hydroxymethyl)cyclobutyl]carbamate, a Boc-protected gem-difluorocyclobutane aminomethyl building block. The gem-difluoro group enhances metabolic stability.
ApplicationsPharmaceutical intermediate; fluorinated building block; cyclobutane; Boc-protected

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