tert-butyl N-[3,3-difluoro-1-(hydroxymethyl)cyclobutyl]carbamate

Product No. SL1112006 CAS 1232365-42-2 Purity ≥99%
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tert-butyl N-[3,3-difluoro-1-(hydroxymethyl)cyclobutyl]carbamate structure

Key Properties

Molecular FormulaC10H17F2NO3
Molecular Weight237.24 g/mol
AppearanceYellow solid
SMILESCC(C)(C)OC(=O)NC1(CO)CC(F)(F)C1
InChIKeyRNZVBWMKWVRXIY-UHFFFAOYSA-N
More Properties
EC/List No.846-336-9

Description

tert-Butyl N-[3,3-difluoro-1-(hydroxymethyl)cyclobutyl]carbamate, a Boc-protected gem-difluorocyclobutane aminomethyl building block. The gem-difluoro group enhances metabolic stability.

Applications

Pharmaceutical intermediate; fluorinated building block; cyclobutane; Boc-protected

Structural Feature
Cyclobutane scaffold
Reactive Feature
Boc-protected amine Difluoro substituted Hydroxymethyl group
Synthesis Role
Fluorinated small-ring building block
Application Context
Pharmaceutical intermediate