3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide

Produktnr. SL1112040 CAS 85622-93-1 Reinheit ≥98%
Zu diesem Produkt anfragen Auftragsynthese eines Analogs
3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide structure

Kerneigenschaften

SummenformelC6H6N6O2
Molare Masse194.15 g/mol
AussehenWhite to off-white solid
SMILESCn1nnc2c(C(N)=O)ncn2c1=O
InChIKeyBPEGJWRSRHCHSN-UHFFFAOYSA-N

Gefahrenklasse

GefahrenklasseCarc. 1B; Muta. 1B; Repr. 1B; STOT RE 1; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2

Beschreibung

Temozolomide, an imidazotetrazine antineoplastic agent. Spontaneously degrades at physiological pH to generate a methyldiazonium ion that methylates DNA O6-guanine; used for glioblastoma.

Anwendungen

API; antineoplastic; alkylating agent

Structural Feature
Imidazotetrazine scaffold
Reactive Feature
Carboxamide
Synthesis Role
Alkylating active molecule
Application Context
Active pharmaceutical molecule Antitumor drug related