1-Amino-3-fluorocyclobutanecarboxylic acid

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1-Amino-3-fluorocyclobutanecarboxylic acid structure
Structural Feature
Cyclobutane scaffold
Reactive Feature
Amino acid Carboxylic acid Fluorinated building block
Synthesis Role
Small-ring building block
Application Context
Pharmaceutical intermediate
Product CodeSL1112016
Molecular FormulaC5H8FNO2
Molecular Weight133.12
AppearanceWhite to off-white solid
SMILESNC1(C(=O)O)CC(F)C1
InChIKeyNTEDWGYJNHZKQW-UHFFFAOYSA-N
Description1-Amino-3-fluorocyclobutanecarboxylic acid, a fluorinated α-amino acid building block. Fluorocyclobutane amino acids serve as bioisosteres of natural amino acids for peptide drug modification.
ApplicationsPharmaceutical intermediate; fluorinated building block; amino acid; cyclobutane

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