4-Chloro-7H-pyrrolo[2,3-d]pyrimidine

이 제품 문의하기 유사체 맞춤 합성
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine structure
Structural Feature
Pyrrolopyrimidine scaffold
Reactive Feature
Heteroaryl chloride
Synthesis Role
Kinase inhibitor building block
Application Context
Pharmaceutical intermediate
CAS 번호3680-69-1
분자식C6H4ClN3
분자량153.57 g/mol
외관White crystalline solid
SMILESClc1ncnc2[nH]ccc12
InChIKeyBPTCCCTWWAUJRK-UHFFFAOYSA-N
제품 설명4-Chloro-7H-pyrrolo[2,3-d]pyrimidine, with 4-chloro as a nucleophilic aromatic substitution handle. Condenses with amines to construct pyrrolopyrimidine drugs; key intermediate for JAK inhibitors like tofacitinib.
용도Pharmaceutical intermediate; pyrrolopyrimidine; JAK inhibitor intermediate
위험물 등급Acute Tox. 3 (Oral); Skin Irrit. 2; Eye Irrit. 2; STOT SE 3 (Resp)