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| 基本信息 | |
| 【中文】 芍药苷 |
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| 【英文名称】 ACLITAXEL NSC 178886 peoniflorin Delmacinone Paeony root Paeoniflorm PAEONIFLORIN Paeonia moutan PAEONIFLORIN(P) Paeoniflorin std. Paeoniflorin ,98% Paeoniflorin P.E. 3aα,5α, 5aα,5bα)]- Paeoniflorin Extract White Peony Root P.E. Paeonia lactiflora P.E. PAEONIFLORIN 98+% BY HPLC 5-alpha,5a-alpha,5b-alpha))-a-alph Ramipril (DMF, under registration) Ranitidine (DMF, under registration) Levofloxacin DMF (under registration) Methylprednisolone Acetate, Micronized PACLITAXEL C13 SOLUTION STD 1.0mg/mL(P) β-D-Glucopyranoside,5b-[(benzoyloxy)methyl] Paeoniflorin, froM Paeonia sterniana Fletcher in Journ. 5-methano-1h-3,4-dioxacyclobuta(cd)pentalen-1a(2h)-yl,(1ar-(1a-alpha,2-beta,3 beta-d-glucopyranoside,5b-((benzoyloxy)methyl)tetrahydro-5-hydroxy-2-methyl-2, tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl,[1aR-(1aα,2β (2R,6aβ)-3aβ-(Benzoyloxymethyl)-4-(β-D-glucopyranosyloxy)-5-methyl-2α,5α:3α,4α-dimethanohexahydrofuro[2,3-b]furan-2-ol 5beta-[(Benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1alpha(2H)-yl-beta-D-glucopyranoside 5beta-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1h-3,4-dioxacyclobuta[cd]pentalen-1alpha(2h)-yl-beta-d-glucopyranoside (1aR,2S,3aR,5R,5aR,5bS)-5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl-β-D-glucopyranoside [(1aR)-5bβ-[(Benzoyloxy)methyl]-3aβ,5,5aβ,5b-tetrahydro-5β-hydroxy-2β-methyl-2,5-methano-3,4-dioxa-1H-cyclobuta[cd]pentalen-1a(2H)-yl]β-D-glucopyranoside [(1aR)-5bβ-[(Benzoyloxy)methyl]-3aβ,5,5aβ,5b-tetrahydro-5β-hydroxy-2-methyl-2α,5α-methano-3,4-dioxa-1H-cyclobuta[cd]pentalen-1aβ(2H)-yl]β-D-glucopyranoside β-d-Glucopyranoside, 5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl, [1aR-(1aα,2β,3aα,5α,5aα,5bα)]- beta-d-Glucopyranoside, 5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl, [1aR-(1aalpha,2beta,3aalpha,5alpha,5aalpha,5balpha)]- beta.-d-Glucopyranoside, 5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl, [1aR-(1a.alpha.,2.beta.,3a.alpha.,5.alpha.,5a.alpha.,5b.alpha.)] |
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| 【CAS】 23180-57-6 |
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| 【中文名称】 芍药甙 芍药苷 |
|
| 【EINECS 编号】 245-476-2 |
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| 【分子式】 C23H28O11 |
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| 【MDL 编号】 MFCD00869331 |
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| 【分子量】 480.46 |
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| 【MOL 文件】 23180-57-6.mol |
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| 物理化学性质 | |
| 【外观性质】白色吸湿性无定形粉末。 | |
| 应用领域 | |
| 【用途一】抗心肌缺血、抑制血小板聚集作用；解痉作用；镇痛、镇静作用；抗炎、抗溃疡作用；保肝作用；调节免疫力作用；耐缺氧作用等。临床应用：用于冠心病的治疗；用于老年性疾病，增强体质与免疫功能、抗炎止咳、祛痰平喘等方面，尤其是老年慢性呼吸道疾病的治疗中可作辅助药物。 | |
| 安全数据 | |
| 【海关编码】29389090 | |
| 常见问题列表 | |
| 【应用】芍药苷可抗组织细胞氧化应激损伤、抑制星形胶质细胞的激活、增强保护神经，对于纹状体及黑质多巴胺能神经细胞的损伤具有明显的拮抗作用，并可改善运动迟缓，因而可用于治疗阿尔茨海默症、帕金森病、癫痫等脑部疾病。此外，芍药苷还可以抗肿瘤、类风湿关节炎和强直性脊柱炎等自身免疫性疾病。动物实验还证明芍药苷可明显降低血糖含量、对心肺细胞具有重要的保护作用。 | |
| 【制备】称取40kg白芍药材，用70％乙醇浸泡过夜，回流提取2次，每次2h，滤过，合并滤液，旋转蒸发至无醇味，调整药液使每1ml药液相当于0.5g生药，备用。称取120kg(湿重)LX38树脂，装入不锈钢柱(300×2300cm)中，柱体积为60L，上样，吸附1h后，先用水300L，10％乙醇300L去除杂质，再用50％乙醇360L洗脱芍药苷和白芍苷，最后用95％乙醇再生树脂，流速为150‑200L/h，将50％乙醇部位浓缩蒸干得2.52kg，其中芍药苷纯度为24％，白芍苷为16％。 | |
| 芍药苷价格(试剂级) | ||||||||||||||||
【芍药苷价格(试剂级)】
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